Carbapenem Antibiotics - Meropenem, Imipenem, Ertapenem • Video • MEDtube.net
Carbapenem Antibiotics - Meropenem, Imipenem, Ertapenem • Video • MEDtube.net
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Aazer Nawab on Instagram: "Sodium valproate and meropenem (a carbapenem antibiotic) should not be given together because of a serious drug–drug interaction. -Mechanism of Interaction: •Carbapenems (like meropenem, imipenem, ertapenem) markedly reduce serum concentrations of sodium valproate. •This happens because carbapenems inhibit the hydrolysis of valproate-glucuronide back to valproate in the gut and possibly enhance its elimination. •Result: Rapid fall (within 24 hours) in valproate levels,
Aazer Nawab on Instagram: "Sodium valproate and meropenem (a carbapenem antibiotic) should not be given together because of a serious drug–drug interaction. -Mechanism of Interaction: •Carbapenems (like meropenem, imipenem, ertapenem) markedly reduce serum concentrations of sodium valproate. •This happens because carbapenems inhibit the hydrolysis of valproate-glucuronide back to valproate in the gut and possibly enhance its elimination. •Result: Rapid fall (within 24 hours) in valproate levels,
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