We have discovered two types of 5′ intronic gene mutation that impair androgen receptor (AR) mRNA expression severely, and cause complete androgen insensitivity. Labium majus skin fibroblasts ...

The mutation—a substitution of a conserved proline residue ... High-frequency oscillations activate endosymbiotic gene expression, while low-frequency oscillations modulate phenylpropanoid ...

Recent reports have linked genetic mutations in surfactant protein C (SFTPC ... exonic change resulting in a change in amino acid sequence. In this case, a T to C substitution resulted in a change in ...

DNA vaccines offer another promising improvement to conventional ... Bacteriophages can replicate in host cells and are able to produce new lytic phages to keep pace with the mutation of pathogens.

Institute of Human Genetics, University of ... phenotype correlations. Specific mutations tend to be strictly associated with either a BM or a UCMD phenotype (tables 1 and 2). The triple helical ...

At temperatures of 0.3 and 0.5, the number of sites designed as harmful mutations was only 4 and 5. It is noteworthy that previous studies have shown that glycine on the luminescent residue group is ...

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of ...

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating ...

A new case report details a novel genetic mutation linked to drug resistance in a non-small cell lung cancer patient ...

A groundbreaking study has uncovered how specific genetic mutations influence cancer treatment outcomes -- insights that could help doctors tailor treatments more effectively. The largest study of its ...

For 30 years, researchers have known that Huntington's is caused by an inherited mutation in the Huntingtin (HTT) gene, but they didn't know how the mutation causes brain cell death.A new study ...