With base substitution mutations, only a single nucleotide within a gene sequence is changed, so only one codon is affected (Figure 1). Insertions and deletions are two other types of mutations ...

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...

This process, called mutation, is part of what determines changes in the characteristics of populations across multiple generations.

“What is quite amazing is that it’s only one amino acid substitution that can make a lot of ... The multitude of experiments “is definitely convincing to me that this single amino acid mutation is ...

In a study published online March 10 in Cancer, authors identified gliomas with mutational signatures associated with ...

“This is the first use of forward and reverse genetics to demonstrate that a specific point mutation in the Zika virus genome can lead to dramatic brain defects in vivo.” A type of flavivirus, Zika ...

SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.