With base substitution mutations, only a single nucleotide within a gene sequence is changed, so only one codon is affected (Figure 1). Insertions and deletions are two other types of mutations ...

The main difficulty in estimating rates of mutation involves the fact that DNA changes are extremely ... estimates should not be confused with substitution rates estimated over phylogenetic ...

The root causes of most forms of Alzheimer's disease largely remain a mystery. Now, researchers have revealed a new piece of ...

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene ...

“What is quite amazing is that it’s only one amino acid substitution ... expressing the human gene produced more basal radial glia and more neurons, strengthening the case for a causal relationship ...

Gene mutations are important in the development ... Simplistically, mutations may involve the substitution, deletion, addition, or rearrangement of base pairs. In some cases, parts of two ...

This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ...

There are many different types of mutations which can arise in DNA. This diagram shows the normal order of the bases for one of the strands in a DNA molecule. Only one of the strands of DNA is ...

Although the genetic interactions among mutations in starch biosynthesis ... leading to an amino acid substitution which ...