Early research shows a one-time gene therapy has potential for addressing both the liver and lung disease that patients with ...

Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...

Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

In a study published online March 10 in Cancer, authors identified gliomas with mutational signatures associated with ...

SARS-CoV-2 secondary structure shapes mutation frequencies, constraining viral evolution models predicting fitness can benefit from integrating secondary structure data.

Having two copies of the MTHFR gene mutation may raise your risk for certain health conditions, though more research is needed. You may have the mutation and not find out unless you undergo ...

His only deficit was on four tests of executive function: the Digit Symbol Substitution Test, Trails A and B, and animal fluency. PiB PET revealed a high amyloid burden of 3.6 SUVR, which would be ...

It can cause symptoms such as breathing problems and hoarseness. Therapy that targets the mutation, such as EGFR inhibitors, may help. “EGFR” stands for “epidermal growth factor receptor.” ...

People with mutations ... by a single change of an amino acid, from isoleucine to valine, at position 197 (I197V) in the protein chain. I197V isn't the only amino acid substitution that ...

People with mutations in this gene exhibit severe speech ... Instead, we have our own unique form characterized by a single change of an amino acid, from isoleucine to valine, at position 197 ...

These findings set the stage for the current studies, which provide the first molecular pictures of KBTBD4 targeting the CoREST complex through interactions induced by both cancer mutations and a ...