Firefighters show higher rates of glioma-linked SBS42 mutational signatures associated with haloalkane exposure, suggesting ...

In a study published online March 10 in Cancer, authors identified gliomas with mutational signatures associated with ...

Early research shows a one-time gene therapy has potential for addressing both the liver and lung disease that patients with ...

Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

The author is looking forward to seeing how Beam Therapeutics would do in their clinical trials of single-base DNA editing.

Acquired DNA mutations found in the SERPINA1 gene can protect liver cells from damage in patients with alpha-1 antitrypsin ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Single-cell multiomic analyses reveal known and new genes and pathways involved in the development of germ cells and provide a discovery platform for the scientific community.

First, common diseases (or high or low quantitative trait values) are generally not as evolutionarily disadvantageous as single-gene disorders, which often cause early death or at least markedly ...

Mar. 10, 2025 — Researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in ...