ArriVent BioPharma Reports Full Year 2024 Financial Results
First clinical data demonstrating robust confirmed responses and CNS anti-tumor activity for firmonertinib in first-line NSCLC EGFR PACC ...
AOL17d
Bird Flu Spread to Humans May Be a Few Mutations Away, but Overall Risk Is Low
Recent research shows the bird flu virus may be just a few mutations away from transmitting more readily to humans, which could elevate risk. If you haven’t yet been sick this winter ...
The Economist21d
Gene editing is already revolutionising research in the laboratory
When the monkeys were single-celled embryos, scientists had used CRISPR editing tools to silence, or “knock out”, a gene that ...
C&EN23d
XGBMUT: Predicting the Functional Impact of Missense Mutations Using an Extreme Gradient Boost Classifier
Laboratory of Molecular Modeling and QSAR, Faculty of Pharmacy, Federal University of Rio de Janeiro, 373 Carlos Chagas Filho Avenue, Rio de Janeiro, Rio de Janeiro 21941-170, Brazil Laboratory of ...
Nature24d
Molecular glue unexpectedly mimics the effect of cancer mutations
These findings set the stage for the current studies, which provide the first molecular pictures of KBTBD4 targeting the CoREST complex through interactions induced by both cancer mutations and a ...