In a phase 1 trial, all 9 patients with renal cell carcinoma treated with a neoantigen-targeting personalized cancer vaccine ...

In the latest study, researchers found the main genetic mutations in renal cell cancer, possibly by using artificial intelligence (AI). The scientists injected mRNA vaccine made against proteins ...

A personalized neoantigen cancer vaccine generated strong immune responses in renal cell carcinoma patients, leading to ...

A phase 1 study of a personalized cancer vaccine demonstrated antitumor immunity in all treated patients with resected renal ...

For decades, scientists have tried to stop cancer by disabling the mutated proteins that are found in tumors. But many cancers manage to overcome this and continue growing. Now, scientists think they ...

Lung cancer is the leading cause of cancer death worldwide with 1.6 million deaths per year (1). Approximately 85% of cases are non-small cell lung cancer (NSCLC), of which lung adenocarcinoma (LUAD) ...

In this study, the researchers modified 20 key imprinting genes individually using a number of different techniques, including frameshift mutations, gene deletions, and regulatory region edits.

The absence of kinase activity due to this truncation likely promotes unregulated cell growth, increasing the tumorigenic potential of the cancer cells. 3.4.3 BRCA2 c.3599_3600del Frameshift Mutation ...

Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, ...

If mutations are in fact responsible for the observed epigenetic changes, this fact could fundamentally change the way we approach anti-aging efforts in the future." ...

Summary: A new study has uncovered a direct link between somatic mutations and epigenetic modifications, challenging established views on aging. Researchers found that random genetic mutations drive ...

When a child develops a brain tumor, early diagnosis is essential. Alan Cohen, M.D., director of pediatric neurosurgery at Johns Hopkins Children’s Center, shares the most common signs and symptoms ...