Oregon Health & Science University, in collaboration with Oregon State University, has discovered the structural organization and protein components of a lipid-transfer complex known as LPD-3.

Lipid nanoparticles (LNPs) are the most clinically advanced delivery vehicle for RNA therapeutics, partly because of established lipid structure–activity relationships focused on formulation potency.

mRNA has recently gained increasing importance and popularity because of its numerous advantages, including the ability to encode specific proteins and the potential for rapid development and ...

A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune response. It can help scientists and engineers expand the use of RNA medicines ...

Scientists have developed a method for analysing the structure of lipid nanoparticles that could be used to improve vaccine and drug delivery, targeting a wide range of health issues. (Nanowerk News) ...

Existing quantitative approaches to describe lipid flip-flop focus on experimental measurements or calculations at the level ...

Scientists have found that 93% of the lipids in brain tissue are distributed differently in the white and gray matter, the subcortex, the visual and motor cortices, and the prefrontal cortex, which is ...

Lipids are fatty compounds that perform a range of essential functions in the body. Phospholipids, steroids, and triglycerides are examples of lipids. Although lipids play an essential role in the ...

In a recent study published in the journal Nature Metabolism, a team of researchers conducted detailed longitudinal profiling and analysis of the lipidome using plasma samples from over a hundred ...

MIT researchers have demonstrated that cell membrane composition directly influences EGFR activity, with elevated negatively ...