Spontaneous mutations tend to reduce fitness in populations of living organisms, but this erosion of fitness is countered by natural selection. This study uses the first mutation accumulation ...

Huntington’s disease is a genetic condition that is inherited in an autosomal dominant pattern. The genetic change that causes Huntington’s disease is a CAG repeat of the huntingtin (HTT) gene, which ...

Childhood cancers are often considered genetically simple, containing few mutations. However, this notion has been challenged in a new study that found an unexpectedly high number of mutations in a ...