Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...

Undruggable targets typically refer to a class of therapeutic targets that are difficult to target through conventional methods or have not yet been targeted, but are of great clinical significance.

In A Nutshell As cells age, they deliberately shrink a major internal structure called the endoplasmic reticulum. This downsizing happens early in adulthood and shifts cells away from protein ...