Proteins are among the most important molecular building blocks of life. They themselves are built from amino acids linked together based on the information in our genetic material. In this process, ...

In a study published in Nature Communications, researchers at Karolinska Institutet have mapped key steps in the assembly of the mitochondrial ribosome, offering new clues to how defects in this ...

The host cell system is a critical determinant of recombinant protein quality and yield, with direct influence on protein folding and post-translational modification factors that shape the ...

A recombinant protein is a protein made by genetically engineered cells rather than extracted directly from its natural source. Scientists insert the gene for the desired protein into a production ...

The functioning of neurons, cells that transmit information in the nervous system, heavily relies on the production of proteins. Proteins are synthesized both inside cells (i.e., in the soma) and ...

The demand for complex therapeutic proteins, is rapidly accelerating, with the bispecific market alone projected to grow to $50B by 2030. While these atypical molecules offer transformative clinical ...

The cost-effective, easy-to-use T7 expression system has been integral to Escherichia coli protein production since its introduction in 1986. Now, a just-developed enhancement is making it even better ...

We may have discovered a fundamental cause of cellular ageing that underlies many other ageing processes in cells. A study of the brains of freshwater fish called killifish has shown that, as they age ...

The aim of this study was to develop a rapid and easy-to-adapt protocol for recombinant production of Orthoflavivirus proteins. We introduced the new-generation pOpiE2 vector for virus-free transient ...

As the global population is expected to approach 9.7 billion by 2050, it remains crucial to ensure the adequate and sustainable production of nutritious food. The demand for protein is especially ...