That point mutation in TKTL1 means that the Neanderthal version of ... “What is quite amazing is that it’s only one amino acid substitution that can make a lot of change. . . . I find it really ...

A mutation is a change in the sequence of ... The most common type of mistake is a point substitution. More uncommon is the failure to copy one of the bases (deletion), the making of two copies ...

With base substitution mutations, only a single nucleotide within ... tells the ribosome to terminate protein synthesis at that point. Consequently, the mutant protein is entirely different ...