Deciphering the conundrum of treatment resistance in metastatic epithelial malignancies is a major unmet medical need. Prostate cancer shows high response rates to androgen deprivation therapy (ADT), ...
Cancer progression is driven by both somatic copy number aberrations (CNAs) and chromatin remodeling, yet little is known about the interplay between these two classes of events in shaping the clonal ...
Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...
Young, Empowered and Strong: A Web-Based Education and Supportive Care Intervention for Young Women With Breast Cancer Across the Care Continuum To overcome these challenges, we have developed a ...