Cancer cells cripple immune cells by donating their damaged mitochondria, hindering the immune response and fostering tumour ...
Mitochondria are well known as the powerhouses of the cell. These crucial, energy generating organelles even have their own little genomes... | Cell And Molecular Biology ...
New research at the University of Alberta may make it easier to diagnose serious diseases that disrupt the body's energy ...
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News Medical on MSNNew mechanism of immune evasion discovered in cancer cellsThe immune system plays a key role in detecting and destroying cancer cells. Cancer immunotherapy works by programming immune cells to recognize and eliminate cancer cells.
Researchers from Japan, discover mitochondrial transfer from cancer cells to immune cells and metabolic reprogramming of the tumor microenvironment as a key immune evasion strategy. Targeting ...
Exonuclease action of replicative polymerase gamma drives damage-induced mitochondrial DNA clearance
How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...
Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...
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News Medical on MSNDecoding the influence of mitochondrial Ca2+ regulation on neurodegenerative disease progressionMitochondria are critical for cellular homeostasis, regulating bioenergetics, redox balance, Ca2+ signaling, and cell death. Mitochondrial Ca2+ (Ca2+mito) plays a dual role in physiological processes ...
This means that the damage has multiple chances to generate harmful mutations, which can lead to cancer. While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms ...
Discover the genetic heritage of the Nicobar Archipelago in the Indian Ocean through a recent study in human genetics.
Mitochondrial defects, however, are associated with the development of diseases such as type 2 diabetes. Patients who suffer from this disorder are unable to produce enough insulin or use the insulin ...
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