B cells play a key role in humoral immune responses through their ability to produce antibodies. In addition, they can also function through other antibody-independent pathways, such as immune ...

The Israeli study examined tumor samples and nearby lymph nodes from 11 patients with high-grade serous ovarian cancer.

However, details of the intervening steps, as researchers have learned in the past 65 years, are quite complex — certain cells carry the flu antigen to the immune system, specific immune cells respond ...

While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It has memory B cells—"trained" immune cells that circulate throughout the ...

The average human has about 1.8 trillion immune cells. These cells patrol the body for bacteria, viruses, cancers, and other threats. Vaccines enhance this security system by teaching our immune cells ...

B cells are a crucial component of immunity, but their function, especially antibody secretion, has largely been studied in the context of secondary lymphoid organs (SLOs) and systemic immune ...

Antibody-mediated rejection (ABMR) remains the leading immunological cause of kidney allograft loss, yet its humoral origins are incompletely understood.

Memory B cells are particularly long-lived and "remember" pathogens, priming the immune system to respond quickly if it encounters the pathogen again. When someone has cancer or a chronic infection, ...

University of Pittsburgh School of Medicine and UPMC Hillman Cancer Center scientists have discovered a novel subset of cancer-fighting immune cells that reside outside of their normal neighborhood – ...

Researchers have uncovered a critical, previously underappreciated role for B cells in vaccine protection. Best known for producing antibodies, B cells also guide other immune cells, specifically CD8 ...

T-bet expression is required for persistence of memory B cells that have rapid differentiation potential to become antibody-producing plasma cells in response to a second infection BIRMINGHAM, Ala. – ...