This TimeCapsule reviews the major transformations in lipid metabolism and cardiovascular disease prevention during the first quarter of the 21st century and their impact on clinical practice. From ...

Lipids are fatty molecules that play critical roles in cell function, including membrane structure, energy storage and nutrient absorption. Most lipids are made in a cell organelle called the ...

Hepatic lipid homeostasis is critical for both cellular function and overall metabolic health. Disruptions in lipid homeostasis can lead to fatty liver diseases, which have become a significant global ...

LC3-associated phagocytosis (LAP) is a specialized process for degrading dead cells, microbes or other particles. It plays a role in innate immunity, inflammation regulation and anticancer responses.

When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body. But they are also involved in regulating the genes expressed within—and the ...

Obesity and obesity-associated diseases, such as type 2 diabetes mellitus and cardiovascular diseases, have reached pandemic levels worldwide and are major threats to human life. Lipid species within ...

Sepsis, a life-threatening condition caused by dysregulated host response to infection, remains a major cause of global mortality. Sepsis-induced cardiac dysfunction (SICD), also known as septic ...

Precise quantification and annotation of individual lipids is critical for understanding the complicated lipid function in biological systems. But achieving both concurrently is challenging.

A team at Helmholtz Munich and the Technical University of Munich (TUM) has developed a new microscopy technique that can distinguish lipid species in living cells – in particular cholesterol and ...