Diacylglycerol kinases (DGKs) constitute a diverse enzyme family that plays a pivotal role in cellular signal transduction by catalysing the phosphorylation of diacylglycerol (DAG) into phosphatidic ...

Enzymes known as kinases play a critical role in cell growth, metabolism and signaling in a multitude of organisms across the tree of life—from algae to helminths to mammals. Now, scientists have ...

Protein kinase inhibitors represent a major advance in cancer treatment due to their ability to target the specific kinases involved in tumor growth and survival. More than 80 small-molecule protein ...