Human leukocyte antigen (HLA) compatibility between donor and recipient is closely related to the clinical outcomes of most solid organ transplantation. However, unlike other solid organ ...
The human leukocyte antigen class I (HLA-I) genotypes have been proven to have an impact on the oncogenic mutational landscape and immunotherapy outcomes in several cancers. However, the HLA-I ...
Post-Transplant Cyclophosphamide–Based Graft-Versus-Host Disease Prophylaxis Attenuates Disparity in Outcomes Between Use of Matched or Mismatched Unrelated Donors The study included 17,292 unrelated ...
Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...
HLAs sit on the surface of cells and have enormous variability from person to person, serving somewhat as molecular fingerprints. When the body encounters unfamiliar versions of these proteins from a ...
When a patient undergoes an organ transplant, failure to match the donor and recipient can lead to the recipient's immune system attacking the new organ, a process triggered by a specific HLA (human ...
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