Nature

Novel polymorphisms and the definition of promoter ‘alleles’ of the tumor necrosis factor and lymphotoxin α loci: inclusion in HLA haplotypes

Tumor necrosis factor (TNF) and lymphotoxin alpha (LTA) influence a variety of cellular responses and play a complex role in the immune response. Several single nucleotide polymorphisms (SNPs) have ...
ascopubs.org

Variation in genetic polymorphisms and gene expression of HLA-E to predict outcomes in metastatic colorectal cancer (mCRC) patients (pts) treated with first-line FOLFIRI ...

Integrating multiple “omics” analyses, on a triage concept, for effective case selection followed by diagnostic colonoscopy. This is an ASCO Meeting Abstract from the 2020 Gastrointestinal Cancers ...
ascopubs.org

Podcast: A Deep Dive Into HLA Typing For Unrelated Donor Hematopoietic Cell Transplantation

This podcast comments on a large registry study evaluating the effect of ultra-high-resolution HLA typing on outcomes of unrelated donor transplantation. For patients who are potential candidates for ...
Medscape

Personalized Medicine for HLA-associated Drug-hypersensitivity Reactions

1 Department of Microbiology & Immunology, The University of Melbourne, Parkville, Victoria 3010, Australia. An increasing number of HLA associations have been observed with drug-hypersensitivity ...