Pore-forming toxins are protein assemblies used by many organisms to disrupt the membranes of target cells. They are expressed as soluble monomers that assemble spontaneously into multimeric pores.

Protein kinases play central roles in cellular regulation by catalyzing the phosphorylation of target proteins. Kinases have inherent structural flexibility allowing them to switch between active and ...

As a possible new anticancer strategy, synthetic biologists have engineered bacteria to secrete a toxic protein that kills surrounding cells when exposed to blue or red light (ACS Synth. Biol. 2014, ...