Clusters of proteins found on neurons are calcium-signaling “hotspots” that link electrical signals to gene expression, allowing neurons to produce crucial proteins. The discovery may potentially lead ...

Voltage‐gated calcium channels, particularly the CaV2.1 channels encoded by the CACNA1A gene, are central to cerebellar function and synaptic transmission. Dysfunction in these channels leads to a ...

Congenital stationary night blindness (CSNB) is caused by mutations in a specific calcium channel. A comprehensive proteomic study by researchers at the University of Innsbruck now reveals how these ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Patients with CaV2.1 channelopathies face severe and often debilitating symptoms, such as seizures, migraines, tremors, and ...

Pretein design researcher Yulai Liu holds an enlarged 3D printed model from his team's efforts to design functioning calcium channels entirely from scratch. He is standing in David Baker's lab at the ...

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...

An essential protein that acts as a gatekeeper for calcium entering cells promotes the growth of oral cancer and generates pain, according to a new study. Targeting this protein -- the ORAI1 calcium ...

Research at UC San Francisco has shown for the first time how the commonly prescribed seizure and pain medication, gabapentin, acts inside of cells, opening the door to new, more effective treatments ...

Calcium may interact with supplements you are taking, such as magnesium and vitamin D, reducing absorption and affecting ...