A new Review reveals how aging can push the immune system into a paradoxical state, weaker against threats yet more prone to attacking the body’s own tissues.

A new review argues that aging may not be just a collection of molecular defects, but a progressive drift in cell identity that links inflammation, fibrosis, mitochondrial damage, and tissue decline.

Every cell in your body runs on a currency called ATP, and the factories that mint it are mitochondria. For decades, scientists knew those factories deteriorated with age. What they could not explain ...

Aging is characterized by the progressive loss of physiological integrity, leading to impaired tissue function and increased vulnerability to chronic diseases. Although the Hedgehog (Hh) signaling ...

An international research team focused on aging reports that urolithin A at 1,000 mg per day shifted human immune profiles toward a more naive-like, less exhausted CD8 + state and increased fatty acid ...

Scientists are no longer just cataloging the damage that comes with age, they are starting to rewire the machinery inside cells that makes that damage accumulate in the first place. A new wave of work ...

Toward the goal of elucidating endocrine system aging mechanisms, this study establishes the first single-cell aging atlas across multiple endocrine organs. The research reveals conserved aging ...

Aging is a serious global social issue and the predominant cause of many aging-related diseases. According to the WHO, 22% of the world’s population (roughly 2 billion people) will be over the age of ...

Improvements in public health have allowed humankind to survive to older ages than ever before, but, for many people, these added golden years are not spent in good health. Aging is a natural part of ...

As we age with each passing year, we become more susceptible to chronic diseases like cancer, heart disease, and dementia. Scientists have long focused on fighting these conditions one at a time.

Promising mouse studies and billions of dollars in funding are stoking excitement. But we’ve been here before.

A newly identified protein may hold the key to rejuvenating aging brain cells. Researchers found that boosting DMTF1 can restore the ability of neural stem cells to regenerate, even when age-related ...